Every Signature. Authenticated. Compliant.
How ESignM – Electronic Signature Management Software by goPLIMS delivers two-factor authentication, uniquely watermarked control copies, and a fully tamper-evident audit trail — all within one integrated, 21 CFR Part 11 compliant platform.
Electronic Signature Management
In regulated industries, a signature is not just an approval — it is a legal and compliance record. Paper-based sign-offs, unverified email approvals, and disconnected external tools create traceability gaps that are difficult and costly to close. ESignM by goPLIMS replaces all of that with a single, integrated platform that combines document management, uniquely watermarked control copies, and two-factor authenticated electronic signatures — built specifically to meet 21 CFR Part 11 requirements.
What is ESignM?
ESignM is a comprehensive, cloud-based electronic signature management platform that combines document management, unique control copy generation, and two-factor electronic signatures in a single integrated system. Built to meet 21 CFR Part 11 compliance requirements, ESignM gives organisations a secure, verifiable, and fully auditable framework for digital approvals — eliminating the need for multiple external tools.
From initiation through to final signed closure, ESignM maintains complete traceability and regulatory integrity. Internal users authenticate via username/password and a goPLIMS app-based OTP. External stakeholders — clients, vendors, and partners — sign securely via an email link and a custom one-time password, with no platform account required.
Built for Regulated Compliance
ESignM is purpose-built to satisfy 21 CFR Part 11 electronic signature and audit trail requirements — delivering the documentation integrity that pharma, life sciences, and regulated industries demand.
What You Can Do with ESignM
ESignM consolidates everything your team needs for compliant digital approvals — from control copy generation to authenticated signature routing — into one integrated workflow.
Watermarked Control Copies
Generate uniquely watermarked control copies of documents with the initiator’s identity embedded — creating a verifiable, tamper-evident record for every approval.
Internal & External Signature Routing
Route documents for electronic signature to both internal team members and external stakeholders — with sequenced, role-based approval workflows for every document.
Two-Factor Authentication
Enforce two-factor authentication for every signer — internal users via app-based OTP, external signatories via secure email link and custom one-time password.
Real-Time Approval Tracking
Track the live status of all approvals, signatures, and control copies centrally — with full visibility of who has signed, who is pending, and what is outstanding.
Two-Factor Authentication & Watermarked Control Copies
ESignM’s most powerful and distinctive capability is its dual-layer security model — combining unique control copy generation with robust two-factor authentication for every signatory, regardless of their location or organisation. Two independent security mechanisms working together — for complete identity assurance on every signature.
Two-Factor Authentication
Internal users: username/password + goPLIMS app-based OTP for every signature action
Two-Factor Authentication
External stakeholders: secure email link + custom one-time password — no platform account needed
Two-Factor Authentication
Every signer identity is positively verified before any signature is accepted
Two-Factor Authentication
All authentication events are automatically logged to the tamper-evident audit trail
Watermarked Control Copies
Each control copy is uniquely watermarked with the initiator’s identity embedded directly into the document
Watermarked Control Copies
All control copies and signed records stored in secure, access-restricted folders
Watermarked Control Copies
Complete, tamper-evident log of all signatures, approvals, and document versions
Watermarked Control Copies
Audit-ready records available for regulatory inspection at any moment
No more paper-based sign-offs. No unverified approvals. No compliance gaps.
Every signature is two-factor authenticated, attributable, traceable, and stored securely — from the first request to final closure.
Built on 3 Core Pillars
SECURE
Enforce two-level authentication for all signers, protect control copies and signed documents in access-restricted folders, and maintain a tamper-evident audit trail for every action.
CONTROL
Generate uniquely watermarked control copies, manage routing and sequencing of approvals, and track the live status of all signatures and control copies centrally in one platform.
E-SIGN
Route documents to internal and external stakeholders, sequence signature workflows online, and complete fully compliant electronic approvals — from any device, anywhere in the world.
Why Teams Choose ESignM
Replace paper-based, printed, and manually chased signature processes with a fully digital workflow
Meet 21 CFR Part 11 compliance requirements for regulated and quality-driven industries
Enable external clients, vendors, and partners to sign securely — without requiring a platform account
Enforce two-factor authentication for every signer — internal and external — on every approval
Generate uniquely watermarked control copies that embed initiator identity into every document
Support remote and globally distributed teams with secure e-signature access 24/7, from any device
About goPLIMS
goPLIMS is an Integrated Project Execution & Management Platform — delivering real-time visibility, workflow governance, and compliance-ready execution across the entire project lifecycle. Purpose-built for pharma and regulated industries, goPLIMS reduces coordination time by up to 50%, helping teams accelerate speed to market.
Ready to Secure Every Signature?
Discover how ESignM brings two-factor authentication, watermarked control copies, and full compliance to your signature approval process.